The deeply rooted puritan moralizing that led to the prohibition has morphed into a sort of health-centered lifestyle that ignores happiness, virtue and the greatest good and rather focuses on avoiding the greatest evil, which has been recognized in the modern world as death.

Death can't be avoided. It is inevitable, and, I would argue, not a bad thing. It is better than living forever in a world such as ours. This doesn't mean that life isn't a great good and inherently dignified and worth protecting. But if we consider death to be the greatest evil, than there is nothing that is worth us dying for. The idea that there is something worth dying for is really important. If there is nothing that transcends our own valuing of our life, I think that our lives are really shallow and the basis for preserving them is only in that they exist already. Then there is no impetus for the good of creating more life.

I would argue that the end of man is to know God and not just to avoid death. And knowing God and, hence, happiness is found not in avoiding and ignoring all things that can be abused, but rather in being firmly in the world and yet of a different substance.

All that to say, it is healthiest for man to consume 400 calories per day (the consumption of excess calories are hard on your body). But that is not the good life. Living forever while barely moving so as to not waste energy cannot be the end of man. Rather, grappling with life's pleasures and learning which ones are legitimate and how to enjoy them in moderation is the active life that can, if excellently lived, result in virtue.